Codeine and promethazine is a mixture drugs utilised to treat cold or allergy indications including runny nose, sneezing, and cough.

The subsequent really serious adverse reactions are described, or described in bigger depth, in other sections:

The concomitant use of anticholinergic medicines with Promethazine with Codeine Oral Solution may perhaps increase threat of urinary retention and/or intense constipation, which can produce paralytic ileus [seeWARNINGS AND PRECAUTIONS (5.

The codeine and promethazine in Promethazine with Codeine Oral Answer may well enhance the frequency of seizures in people with seizure Conditions, and will increase the possibility of seizures happening in other scientific settings connected with seizures.

Circumstances OF USE: The information In this particular database is intended to dietary supplement, not substitute for, the abilities and judgment of Health care industry experts. The knowledge will not be meant to protect all doable takes advantage of, Instructions, safety measures, drug interactions or adverse results, nor must it's construed to point that use of a selected drug is Risk-free, ideal or effective to suit your needs or any one else.

The concomitant use of Promethazine with Codeine Oral Remedy with all cytochrome P450 3A4 inducers or discontinuation of the cytochrome P450 3A4 inhibitor could bring about decreased codeine ranges, larger norcodeine stages, and fewer metabolism by way of 2D6 with resultant decrease morphine levels. This can be linked with a lessen in efficacy, and in a few patients, may bring about signs and signs of opioid withdrawal.

Facts Human Information Printed details from scenario Handle and observational scientific tests on codeine use through pregnancy are inconsistent within their conclusions. Some reports of codeine publicity showed an increased chance of Total congenital malformations while others did not.

To help you avoid withdrawal, your doctor may decreased your dose slowly but surely. Withdrawal is more possible When you've got made use of this medication for a very long time (more than a few weeks) or in significant doses. Explain to your health care provider or pharmacist without delay For those who have withdrawal.

Thoroughly evaluate the dose utilizing a Specific measuring machine/spoon. Tend not to utilize a home spoon simply because you may well not get the proper dose.

The codeine and promethazine in Promethazine with Codeine Oral Option may perhaps increase the frequency of seizures in individuals with seizure disorders, and should raise the hazard of seizures occurring in other medical settings involved with seizures.

This medication could make you far more delicate towards the Solar. Limit your time and effort in the Sunlight. Prevent tanning booths and sunlamps. Use sunscreen and have on protective clothing when outdoors. Notify your doctor immediately if you can get sunburned or have pores and skin blisters/redness.

There is absolutely no general read more arrangement about particular pharmacological treatment method regimens for uncomplicated NMS.

Never ever share this medication with A further human being, In particular someone with a history of drug abuse or dependancy. MISUSE Could potentially cause Habit, OVERDOSE, OR Loss of life. Keep the drugs in an area in which Other people cannot reach it. Offering or gifting away this drugs is in opposition to the regulation.

Extended use of opioids throughout pregnancy might trigger neonatal opioid withdrawal syndrome [see Warnings and Safety measures ( five.19) and Clinical Concerns]. There are no accessible data with Promethazine with Codeine Oral Alternative use in pregnant Ladies to tell a drug-linked danger for adverse developmental results. Revealed research with codeine have claimed inconsistent results and have significant methodological constraints (see Information). There are actually stories of respiratory depression when codeine is applied in the course of labor and delivery (see Medical Considerations). Reproductive toxicity scientific tests have not been carried out with Promethazine with Codeine Oral Solution; even so, studies can be obtained with individual active substances (see Data).